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Wednesday October 19, 2005

8:00 AM - 9:00 PM	Registration
9:00 AM - 5:00 PM	Tutorials
6:00 PM - 7:00 PM	Welcome and keynote lecture Using fluorescence to study the E. coli chemotaxis signaling pathway Howard Berg (Harvard University)
7:00 PM - 8:30 PM	Opening Reception

Thursday October 20, 2005

8:00 AM - 5:00 PM	Registration
9:00 AM	Opening Remarks Peter Sorger (Massachusetts Institute of Technology)
	Session I: Biology by Design
	Integrating synthetic biology and systems biology J. J. Collins (Boston University)
	Programming bacteria: wiring synthetic sensors and circuits to heterologous outputs Christopher Voigt (University of California, San Francisco)
	Tuning noise in global gene expression Jeffrey Tabor (University of Texas at Austin)
	Engineering bacteria for production of an anti-malarial drug Jay Keasling (University of California, Berkeley)
Lunch
1:30 PM	Session II: Evolution in Action
	Laboratory models of protocell structure and behavior Jack Szostak (Howard Hughes Medical Institute and Massachusetts General Hospital)
	Genotype to fitness phenotype mapping and the evolution of regulatory networks during experimental evolution in Escherichia coli Dominique Schneider (Université Joseph Fourier)
	Evolving engineering systems Hod Lipson (Cornell University)
	Understanding metabolic networking in microbial consortia by flux balancing, kinetic modeling and experimental validation Vitor Martins dos Santos (German Research Centre for Biotechnology)
	Social amoebae as model systems for genetics and evolution of social interactions Joan Strassmann (Rice University)
5:00 PM	Keynote Lecture Synchronization, singularities and circadian clocks: lessons from Art Winfree's pre-molecular approach to systems biology Steven Strogatz (Cornell University)
6:00 - 8:00 PM	Poster session and reception

Friday October 21, 2005

9:00 AM	Session III: Intracellular Networks
	Dissecting signaling networks using cell perturbations and fluorescence imaging Tobias Meyer (Stanford University)
	Systems biology of cytokine networks Peter Sorger (Massachusetts Institute of Technology)
	Modeling conservation and variation in regulatory networks Daphne Koller (Stanford University)
	Precise intracellular spatial sensing through GTPase cascades Jörg Stelling (ETH Zürich)
	Evolutionary information specifying protein folding and function Rama Ranganathan (Howard Hughes Medical Institute and University of Texas Southwestern Medical Center)
Lunch
2:00 PM	Session IV: Intracellular Dynamics and Multicellular Networks
	Gene circuits and differentiation at the single-cell level: slow, noisy, and out of control Michael Elowitz (California Institute of Technology)
	Maternal gradients and size regulation in insect embryos Eric Wieschaus (Howard Hughes Medical Institute and Princeton University)
	Modeling threshold response to a morphogen gradient Naama Barkai (Weizmann Institute of Science)
	System-level identification of mammalian circadian clocks Hiroki Ueda (RIKEN)
	Using mathematical modeling to help decode biological circuits Claire Tomlin (Stanford University)
5:30 - 7:30 PM	Poster session and reception
7:30 PM	Student Symposium

Saturday, October 22, 2005

9:00 AM	Session V: Mechanics and Scale in Cellular Behavior
	Pushing ahead: force generation and large-scale self-organization by growing actin filament networks Julie Theriot (Stanford University)
	Simulating the interphase microtubule organization in fission yeast François Nédélec (European Molecular Biology Laboratory, Heidelberg)
	Universal scaling laws in biology from genomes to ecosystems: towards a quantitative unifying theory of biological structure and organization Geoffrey West (Santa Fe Institute and Los Alamos National Laboratory)
	Rab-5 endosome movement as a regulated random walk Yannis Kalaidzidis (Max Planck Institute of Molecular Cell Biology and Genetics, Dresden)
	Cell size control networks Mike Tyers (Samuel Lunenfeld Research Institute and University of Toronto)
Lunch
2:00 PM	Session VI: Multicellular Networks and Intracellular Dynamics
	Comprehensive and realistic modeling of biological systems: what, how and why David Harel (Weizmann Institute of Science)
	Cellular nutrient homeostasis Erin O'Shea (Howard Hughes Medical Institute and Harvard University)
	Anticipation and response in cell signaling Mukund Thattai (National Centre for Biological Sciences, Bangalore)
	Dynamical properties of the yeast cell cycle network Chao Tang (University of California, San Francisco)
5:10 PM	Keynote Lecture Getting the message through: reliable communication among bacteria Bonnie Bassler (Howard Hughes Medical Institute and Princeton University)
6:10 PM	Closing Remarks Marc Kirschner (Harvard University)

Sunday October 23, 2005 and Monday October 24, 2005

9:00 AM - 5:00 PM	Workshops